Muscular+Dystrophy+EP

muscular dystrophy- weakness of them muscles as individual muscle cells die. sex linked disorder. a boy gets it because he doesnt have another X chromosome that the dystrophy can mutate and copy on. males get it from there mother when the gene is mutated. a female is a carrier because it can be copied and has another X chromosome to fall back on. females however cannot get the disproder. they are just a carrier.

from a small mutation in one the genes of the X chromosome exons contain instructions for making dystrophin. most boys are missing the exon. this destroys the instructions of the protein being made. the DMD will be missing making the protein stop in the gene. the gene shifts making an unusual codon alignment. the T-A-G tells them when to stop. this makes it stop in mid point of the gene. it shortens the gene leaving cells lost with proteins and then being destroyed. the cell will recognize that the protein isnt right so it degrades it. muscle is not made but fat and connective tissue take up those spaces.