Lucy+diabetes+article

What are the key players in Diabetes? Why?
 * The pancreas, the liver, muscle and fat. All of these help regulate glucose, the amount of sugar in the blood, the amount that is absorb in the cells and how much is released from the energy storage.

What are the unexpected key players in Diabetes? Why? In the gut, there is sugar because thats where food comes in through. They only found in obese mice that there was an inflammation of the immune system. Explain the connection between bones and fat? Explain the connection between bones and the pancreas? Explain the connection between the brain and diabetes. Explain the connection between the immune system and diabetes? Now summarize the article in a paragraph.
 * A hormone from the skeleton that signals from the immune system, the brain and the gut.
 * A hormone produced by fat, is an important regulator of bone, metabolism. They hypothesized that if the fat regulates bones, bone in essence must regulate fat. Lepin, a hormone, is created by fat and helps regulate bone metabolism.
 * There was a substance called osteocaicin, found while working with mice, which is produced by bones and signals fat cells and the pancreas. It helps the body move glucose from the bloodstream into the cells of the muscle and liver. It can be used for energy or stored for later use. The insulin in people are important for regulating lipids. Sooner or later the insulin in the pancreas decreases.
 * The Brain was said to be important in blood sugar regulation. Glucose is a critical fuel for the brain. The brain signals letting you know if there is too much or too little insulin. It there is too little, the liver will have to make more.
 * Macrophages, immune cells, are found in fat tissue. They can cause inflammation, which leads to type 2 diabetes because it is liked to insulin resistance.
 * The body's ablity to produce glucose has been proven to be more complicated than it may have seemed. Diabetes, the fifth leading cause of death, is a disease you get when your body fails to regulate glucose or blood sugar. There have been several new researches, one suggested that a hormone from the skeleton may benefit how body handles sugar, another showed that a hormone releases from the bone may help regulate the blood glucose and also a hormone from fat can help regulate the bone metabolism. The scientist have done test on mice, trying to figure out the effects of these hormones. When testing the mice, they were trying to see if fat, for example, regulates the mice bones. So when they were working with mice they found a substance called ostecaicin. Its produced by the bone, signaling the fat cells and the pancreas. So basically they are running these test to see how well the insulin is handled in the bodies. Later they found another suspect in glucose regulation. It was found in the immune system. The immune cells cause inflammation. Being obese, having inflammation it may cause a resistance in insulin. Glucose is a critical fuel for the brain but not a role in regulating glucose. Other researchers have found that three fatty acids, signal directly to a part in the brain which also regulates appetite, temperature ans sex drive. "If the brain is getting the message that you have adequate amounts of these hormones and nutrients, it will constrain glucose production by teh liver and keep blood glucose relatively low.