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For each of the following define their function and include their role in immunity (the ability to combat disease). (p.127-128)  1. Red bone marrow  a.  In your bones, produces blood cells, and white blood cells. White blood cells are for immunity.  2. thymus gland  a.  make hormones, the T cells also mature here. It makes sure that only T cells that kill harmful cells are around and mature  3. spleen  a.  filters blood, there are macrophages in them, they eat all the bad cells covered in antibodies.  4. lymph nodes  a.  they get bigger when you are sick, they are in your neck, your armpits, and groin. Colonel expansion happens here of b and t cells Describe the barriers to entry and include their role in immunity  1. Skin and mucous membranes  a.  This is the first layer of defense. Lungs are mucous membranes. A physical barrier  2. Chemical Barriers  a.  Tears, sweat, saliva, oil, mucous resident bacteria, another physical barrier that helps
 * Immune System Wiki Homework. (Chapter 7) **
 * 7.2 Lymphatic System **
 * 7.3 Nonspecific Defenses (p. 128-130) **

Define the players in the inflammatory response histamine makes your capillaries leaky, your white blood cells and antibodies cant get where they need to go. runny nose is often a symptom mast cells they release histamine pus yellow white substance that are made of white blood cells. it is a sign of an infection cytokines a chemical that attracts the white blood cells to the region they need to go. macrophages. big eaters that eat anything covered in antibodies that are bad List the four steps in the inflammatory response (figure 7.9) damaged tissues release histamines and they release cytokines to the infected area. **histamines cause capillaries to leak releasing phagocytes and clotting factors into the wound the white blood cells move towards site of the injury. swelling redness** Describe the complement system and its role in immunity. **proteins found in your blood that complement individual immune reactions. they complement your immune system, they trigger mast cells to release histamine. they can cover pathogens and cover things that have antibodies.** Describe the membrane attack complex and its role in immunity. **made of compliment proteins that drill holes in pathogens made of complement proteins in the blood** Describe interferon and its role in immunity. if a cell is infected with a virus, interferon is something a cell will produce to protect their neighbors. Define Antigens. How does specific defense differ from nonspecific defense? Which blood cells are mainly responsible for specific defense, and how do they function? (make a table like the one on page 130) What is acquired immunity? What is active immunity and explain an example? What is passive immunity and explain an example? When is the immune system hypersensitive? Explain how an allergy is an example of hypersensitivity. Explain how tissue rejection is an example of hypersensitivity. Define autoimmune disease. Define the following autoimmune diseases. multiple sclerosis (MS) lupus rheumatoid arthritis
 * 7.4 Specific Defenses (pp.130) **
 * 7.5 Acquired Immunity (pp.136) **
 * 7. 6 Hypersensitivity Reactions (pp.138-139) **