Human+Chromosomes+WB


 * Changes in Chromosome Number
 * Vocab: nondisjunction, trisomy, monosomy, Barr body, Down Syndrome, Turner Syndrome, Klinefelter Syndrome, Poly-X Females, Jacobs Syndrome
 * What are the two types of chromosomes and how many of each do we have in every cell?
 * Describe process that can change the normal number of chromosomes in a cell?
 * Name chromosome disorders due to an abnormal number of autosomal chromosomes.
 * Name chromosome disorders due to an abnormal number of sex chromosomes.
 * Changes in Chromosome Structure
 * Vocab: deletion, duplication, inversion, translocation, Williams syndrome, Crit du Chat syndrome, Alagille sydnrome, Chronic myelogenous leukemia, Burkett lymphoma
 * Name chromosome deletion syndromes.
 * Name chromosome translocation syndromes.

1. Nondisjunction: Sister chromatids fail to separate. Trisomy: Chromosomes with three copies. Monosomy: Chromosomes with a single copy. Barr Body: X chromosome turns to a lump of chromatid. Down syndrome: Trisomy of 21 chromosomes. Turner syndrome: Zygote with one X chromosome. Klinefelter syndrome: XXY chromosome Poly-X Females: Two X chromosomes and extra barr bodies Jacobs syndrome: Two Y chromosomes and one X chromosome.

2. The two types of chromosomes are X and Y. Female cells have XX and males have XY. 3. Nondisjunction changes the number of chromosomes. 4. Down syndrome occurs due to abnormal numbers of autosomal chromosomes. 5. Turner and Klinefelter syndrome occur due to an abnormal number of sex chromosomes. 6. Deletion: The end of a chromosome breaks off. Duplication: Chromosome segments found multiple times in the same chromosome. Inversion: Segment of a chromosome is turned backwards. Translocation: Moving of a segment from one chromosome to another. Williams syndrome: Chromosome 7 breaks off. Crit Du Chat: Chromosome 5 breaks off. Alagille syndrome: Chromsome 20 is removed. Chronic myelogenous lymphoma: Parts of chromosome 22 moves to chromosome 9. Burkett lymphoma: Translocation from part of chromosome 8 to chromosome 14.

7. Alagille syndrome is a chromosome deletion syndrome. 8. Chromosome translocation syndromes are chronic myelogenous lymphoma and Burkett lymphoma.