HIV+NOTES+TFL

1952- Hershey and Chase experiment. - The virus requires any cells to host. Bacterium is a lot smaller than the host cell. Viruses carry and inject genetic material that is carried in a protein shell. There is DNA and RNA viruses After the virus is injected, the host cell replicates the DNA or RNA and assembles more viruses. A dude did an experiment and he made the protein coat radioactive and the DNA radioactive. The radioactive DNA was found inside of the host cell. Then he knew it was the DNA. Part 2: How HIV Replicates- HIV infects the white blood cells of peeps. HIV infection causes AIDS because it weakens the immune system. HIV has RNA as it’s genetic material. It also has a round protein coat and a membrane coat which is studded with proteins. HIV matches up with the Helper T-Cell (lock and key proteins where the receptor is the lock and HIV is the key) Human Cell: DNA - RNA - protein. Virus- virus RNA - virus DNA (integrated) - Human DNA HIV enzyme called reverse transcriptase- turns RNA to DNA. The DNA of the virus turns into your DNA, it’s a permanent resident of your DNA. The cell uses your DNA to produce more viruses. Then it shoots more viruses all over you Part 3 Treatment of HIV: Reverse transcriptase turns RNA to DNA AZT drug kills the enzyme, which blocks the receptors and bounces off. blocks the receptor and stops reverse transcriptase. There is no vaccine and this is because the virus changes so quickly. Part 4 Mutation and HIV HIV has the capacity to evolve no matter what you give it. There are 19 drugs on the market today for the struggle against the stop of HIV. It keeps evolving when one of the drugs while it is out. The virus is constantly changing due to Natural Selection in the patient’s body. Evolution also affects the HIV virus. The virus replicates a very fast, and each time it reproduces random mutations result in slightly different versions of the virus which are then injected into the blood stream. They then are resistant to the drugs because they are different from before. There is no predictability for the HIV virus, making it impossible to treat it. In 1997 Researcher may have discovered a way to almost beat natural selection. The patient is taken off medication and after three months the population of the HIV virus became susceptible to the medicine. After the patient was taken off medication, the virus adapted to the ‘drug-free’ environment and then the scientists hit the vulnerable virus with all of the medicines.
 * Viruses ** :