Diabetes+Article-CMP

=Diabetes Article Assessment **(on Halloween... the best day ever!)**= The "key players" in Diabetes are the pancreas, the liver, muscles, and fat. The reason that each of these are important is because they control the regulation of glucose in the human body. The "unexpected key players" are hormones from the skeleton, that influence how the body handles sugar. Researchers didn't know that the skeleton was part of the endocrine system until recently, so insubstantial research has been preformed it. Thanks to Dr. Saul Malozowiski, researchers now know that the skeleton is actually and endocrine organ, which produces hormoes that act outside of the bone. Leptin, a hormone that is produce by fat, regulates metabolism in the bones. "If fat regulates bone, bone in essence must regulate fat," said Dr. Gerard Karsenty. In experimenting with mice, Dr. Kartensty discovered that osteocalcin (a production of the bone), acted by signaling fat cells as well as signaling the pancreas. This hormone helps move glucose into the cells of the muscles and liver, through the bloodstream. It can then be stored or used for energy in the future. Through his research, Kartensty also discovered that osteocalcin made the mice more sensitive to insulin and increased their insulin production, eventually leading to a decrease in their blood pressure. as a bonus, it also significantly helped lower the amount of obesity in the mice. In the human body, osteocalcin signals the activation of the pancreas. Receptors in the brain are what regulate glucose properly, and if these receptors aren't working properly, then glucose levels go out of control and cause diabetes. If inflamed immune cells are activated, resistance to insulin occurs and causes diabetes. In the small intestine, there is a hormone called incretin that serve the purpose of signaling the brain and pancreas to control appetite and lower blood sugar.
 * What are the key players in Diabetes? Why?**
 * What are the unexpected key players in Diabetes? Why?**
 * Explain the connection between bones and fat?**
 * Explain the connection between bones and the pancreas?**
 * Explain the connection between the brain and diabetes.**
 * Explain the connection between the immune system and diabetes?**

=Article Summary (in one paragraph):= In recent years, researchers and scientists have discovered new information that can help lead to the cure for diabetes, rather than its temporary stabilization. One of the main pieces of information that has been learned is that the skeleton is part of the endocrine syst