AP+Death+By+Design+Notes

Death By Design Notes: - Cancer cells don't commit sucide - Cancer cells bypass Programed Cell Death (PCD) and continue to divide and make tumor What is a cell? Communication from cell to cell: - PCD requires the cell to make molecules to kill itself it participates in its own death - cell starts PCD when "told" to die - cancer cells are told to die: they just dont listen
 * Leevmenhoek
 * he would look at a onion
 * he would look at plant cells
 * look like a bubble
 * People don't have walls
 * they eat other cells
 * do things that animals do
 * they come together as a community (called animals and plants)
 * organisms are made of many cells that have to work together
 * community of cells have to interact
 * cells have to become different kinds of cells (muscle, nerve etc.)
 * uni- cellular: single cell
 * mulit-cellular: made of many cells
 * came much later (during evolution)
 * they have to know each other and talk to each other
 * they send signals to each other
 * cancer cells don't "listen" to signals
 * cells don't do anything unless signaled to
 * cells are signaling to each other to divide or don't divide, move or don't move, grow or don't grow
 * cells only divide when new cells are needed
 * for cells to stay alive they need to signals to tell them to stay alive and if they dont get that signal then they die, kill themselves
 * example:
 * put on cell in a dish- it dies and kills itself because it doesnt get the signal to stay alive

Cell Division
 * divides the cell into two

- when in the womb you have webbed feet and hands and when born the cells in between your fingers and toes dies - ppl who still have webbed feet or fingers, the cells in between were never told to die - analogy: when making an animal you have to kill, destroy, remove the scaffolding - humans: 10 to the 13th cells - worms: 959 cells -immortal cell: i never dies DNA damage: radiation, sun, smoking, chemicals in digestive system

Why make a cell if you are going to tell it to die? - probably because that cell had a purpose in an ancestor but not now!