NN+Cystic+Fibrosis+Research

Del.icio.us tag: Humanbiocysticfibrosis

Causes and Effects

 * Cystic fibrosis is an inherited disease
 * the cause was discovered in 1989
 * it is recessive (1 in 25 Caucasians are carriers especially Caucasians from Northern Europe)
 * the most common, fatal genetic disease in the United States
 * to get CF both parents must be carriers, and even then you can still not get CF
 * 25% chance a child will get CF
 * 50% chance a child will be a carrier
 * 25% chance a child will not have CF or be a carrier
 * results from a mutation on chromosome 7
 * chromosome 7 affects the development of a protein called the cystic fibrosis transmembrane regulator (CFTR)
 * cystic fibrosis causes the development of either deformed protein or no protein, resulting in thick, sticky mucus rather than the normal watery mucus produced by regular CFTR protein
 * there are hundreds of different mutations that can result in cystic fibrosis. not all of these mutations are none
 * people with a close family member with CF have an increased chance of being a carrier
 * Cystic Fibrosis can result in: //Staphylococcus aureus//, //Pseudomonas aeruginosa//, //Haemophilus influenzae,// and //Burkholderia cepacia//
 * common diseases that often affect people with cystic fibrosis
 * affects the different parts of the body including: lungs, pancreas, liver, intestines, sinuses and sex organs.
 * thick mucus provides ideal environment for the growth of certain bacteria
 * The mutated chromosome affect the transfer of sodium chloride in certain cells
 * causes thick mucus in the lungs and reproductive system
 * also increases the salt in sweat
 * also creates an imbalance of fatty acids