DH+cancer+notes

10^13 cells 10,000,000,000,000

DNA damage (radiation - sun, smoke, chemicals) immortal cell - it never dies protection from cancer PCD --> programmed cell death 2 genes (gene has the information for a protein) proto-oncogenes (encourage cell division) tumor supressors (p53) (stop cell division) these two genes are damaged in cancer cells proto-oncyogene normally --> encourages cell division After DNA damage oncogene --> and cell division goes crazy

Tumor supressor normally inhibits cell division after DNA damage No longer inhibits cell division

Cells that are cancer cells weird cells -ends of their DNA (tilomeres) never get shorter -weird large nucleus -no function except to divide -cancer cells can pile up on each other. normal cells stop dividing if they touch another cell. So, cancer cells make tumors